Autoimmune liver diseases are chronic, inflammatory diseases that usually progress slowly. The three main categories of autoimmune liver disease are autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC).
Autoimmune hepatitis is a liver disease with no known cause but is considered an “autoimmune” disorder because the immune system attacks the body’s own hepatocytes (liver cells).
Primary biliary cholangitis (PBC) is also a liver disease with no known cause but is believed to be related to other autoimmune disorders. Primary biliary cholangitis begins with inflammation of the small bile ducts. The inflammation blocks the flow of bile out of the liver and liver cells, causing inflammation. As inflammation spreads, scar tissue (fibrosis) develops throughout the liver, replacing more and more liver tissue with fibrosis (scarring), leading to cirrhosis in some cases.
Primary Sclerosing Cholangitis (PSC) is a disease of the large bile ducts in which they become inflamed and heavily scarred. Its cause is unknown and at this time there is no treatment known to stop the disease from progressing.
Call Arizona Liver Health at 480-470-4000 to set up an appointment with one of our experienced providers who can help diagnose your liver condition and put you on a path toward improved outcomes.